Although bloodstone is not explicitly referenced in the Bible, its symbolic resonance can be discerned by examining the biblical motifs of stones and blood. Stones in scripture often signify strength, permanence, and acts of remembrance (e.g., Joshua 4:20-24, where stones commemorate God's intervention). Blood, on the other hand, is a profound symbol of life, covenant, sacrifice, and redemption (see Hebrews 9:22). The fusion of these two motifs in bloodstone—a stone flecked with red—evokes steadfast faith, the endurance of spiritual trials, and the transformative power of sacrificial love. Medieval Christian tradition even linked bloodstone to the blood of Christ, further deepening its association with martyrdom and divine sacrifice.

Although bloodstone is not a traditional Buddhist symbol, stones in Buddhism often represent steadfastness and the enduring nature of the Dharma. The red flecks in bloodstone can be seen as reminders of compassion (karuna) and the suffering inherent in samsara, while the green base symbolizes vitality and growth. Thus, bloodstone may be interpreted as the transformation of suffering into wisdom and compassion, and the cultivation of resilience and equanimity on the path to enlightenment.

Across cultures, bloodstone has been revered as a talisman of protection, healing, and courage. In ancient Greece and Rome, it was believed to staunch bleeding and protect warriors in battle. Medieval Europe called it the 'martyr's stone,' associating it with Christ's blood and the endurance of saints. In modern times, bloodstone continues to symbolize resilience, health, and the archetype of the wounded healer—one who finds wisdom and strength through adversity and suffering.

In Hindu tradition, gemstones are believed to possess specific energies and are used for healing and spiritual protection. Bloodstone (sometimes called 'Ashmagarbha') is associated with the root chakra (Muladhara), grounding, and the purification of blood and energy. It is said to enhance courage, dispel negativity, and support adherence to one's dharma (righteous duty). Dreaming of bloodstone may indicate a need to strengthen one's foundations, purify intentions, or summon courage to overcome obstacles on the spiritual journey.

While bloodstone is not specifically mentioned in Islamic scripture or tradition, stones in general are revered for their spiritual and protective qualities—most notably the aqeeq (agate) ring of the Prophet Muhammad (peace be upon him). The green and red hues of bloodstone can be interpreted as symbols of vitality, life, and the sacrifices made in the path of righteousness. Blood in Islam is closely tied to the sanctity of life and the concept of martyrdom, while stones represent steadfastness and remembrance. Thus, bloodstone may serve as a reminder of spiritual resilience, protection from harm, and the importance of perseverance through trials, aligning with broader Islamic values.

From a Jungian perspective, stones often symbolize the Self—representing stability, wholeness, and the enduring foundation of the psyche. Blood is emblematic of vitality, passion, and the animating force of life. Bloodstone, therefore, may represent the integration of emotional vitality with inner strength, or the process of healing deep psychological wounds. Dreaming of bloodstone could indicate the emergence of latent inner resources, a call for grounding during emotional turbulence, or the transformative confrontation of trauma, leading to psychological renewal.

Spiritually, bloodstone has long been regarded as a potent stone for healing, purification, and courage. It is believed to transmute negative energies, ground spiritual insights into the physical realm, and foster resilience in the face of adversity. In dreams, bloodstone may herald a period of spiritual renewal, signal the need for protection, or awaken dormant healing abilities, guiding the dreamer toward greater wholeness and balance.